The current Phase 2b trial is a double blind, randomized, multicenter, non-inferiority, repeated dose study CG100649 compared with celecoxib in OA patients here . This is the first time that the effectiveness of the OA CG100649 is tested directly against celecoxib in the same clinical trial. As CG100649 had high efficacy at 1, study, onlyay in phase showed 2a OA study is assumed that doses of 2 mg / day and 4 mg / day show in the Phase 2b study is that CG100649 is at least comparable to celecoxib with respect to the efficacy. If the initial hypothesis is supported, additional tests to check whether CG100649 efficacy compared to efficacy compared to celecoxib. Biomarker results from two previous clinical pharmacology studies in healthy volunteers showed that CG100649 may produce efficacy results celecoxib celecoxib in this Phase 2b study.

An estimated 8 to 10,000 patients in the United States alone suffer from peripheral arterial disease , blockages blockages in the blood vessels of the peripheral vascular system and associated with high morbidity. PTA balloon catheters to to open blocked arteries, peripheral angioplasty and stenting procedures.

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