It really is a poster kid for personalized cancers therapy.’.. Clinical trial shows effectiveness of ponatinib in patients with leukemia and lymphoma Huntsman Cancer Institute experts Michael Deininger, M.D., Ph.D., and Thomas O'Hare, Ph.D., were part of a group that discovered a potent oral drug, ponatinib, effective in patients who have developed resistance to standard remedies for chronic myeloid leukemia and Philadelphia chromosome positive acute lymphoblastic lymphoma . Today The New England Journal of Medicine released results of the trial. In the stage I clinical trial executed nationwide at five cancer centers, ponatinib was highly active in sufferers with CML and Ph+ ALL who had developed resistance to currently approved tyrosine kinase inhibitors , the typical treatment for Ph+ and CML ALL.In his new part, Caforio shall are accountable to Lamberto Andreotti, ceo, and has been named a member of the business’s Senior Management Team. Bancroft will increase his role of Chief Financial Officer operational responsibility for the pharmaceutical business in Latin America, Middle East, Africa, Canada, Japan and several other countries in the Pacific Rim. Cazala shall add responsibility for global policy to her function leading Global Commercialization, Europe and Emerging Markets. Anthony C. Hooper, senior vice president, Commercial Operations, and president, U.S., Japan and Intercontinental, has decided to leave the ongoing company. A concentrate on developing skill at all amounts is a key component of our Bristol-Myers Squibb culture, Andreotti said.