Eosinophilic disorders tend to be severe and more persistent than other, even more familiar food allergy symptoms, stated pediatric allergist Jonathan M. Spergel, M.D., Ph.D., director of the Center for Pediatric Eosinophilic Disorders at The Kids's Hospital of Philadelphia . Spergel added that eosinophilic disorders have got only recently been recognized as distinct conditions. The often painful disorders involve swelling and inflammation, and could cause weight loss, vomiting, diarrhea, acid reflux and swallowing difficulties. Any age can be suffering from them group, but tend to be first discovered in kids having feeding failure and difficulties to thrive.The researchers say it is necessary to improve the patients' quality of life because most will take tyrosine kinase inhibitors for the others of their lives. Their study appeared in the April problem of Supportive Care in Tumor. Related StoriesTargeting exhausted immune cells may change prognosis for leukemia relapse patients after transplantBlocking the creation of CHD4 protein may help increase effectiveness of AML treatmentsProtein-coding gene identified as tumor suppressor for severe myeloid leukemia ‘Although much less toxic than the remedies they changed, tyrosine kinase inhibitors, such as for example imatinib, dasatinib or nilotinib, do trigger symptoms that adversely influence a patient's quality of life,’ said study senior writer Paul B.