Antibiotic resistance potentially threatens the efficacy and safety of surgical procedures and immunosuppression therapies By Kate Bass BSc This week The Lancet Infectious Diseases journal published the strongest evidence to time that increasing antibiotic resistance could have disastrous consequences for patients undergoing surgery or cancer chemotherapy sildenafil citrate . Based on a review of published literature, researchers predict a 30 percent reduction in the efficacy of the prophylactic antibiotics routinely given when these methods are performed could result in 120,000 more attacks and 6300 infection-related deaths every year in the USA alone.