Rome requirements : Ankylosing spondylitis exists if bilateral sacroiliitis is definitely associated with the following criteria: Lower back pain and stiffness for a lot more than three months Discomfort and stiffness in the thoracic region Limited motion in the lumbar area Limited chest expansion History of evidence of iritis or circumstances that derive from iritis New York criteria : Definite ankylosing spondylitis exists if advanced-to-severe bilateral sacroiliitis is connected with at least one of the clinical requirements below or if advanced-to-severe unilateral sacroiliitis or moderate bilateral sacroiliitis is certainly connected with clinical criterion 1 or with both scientific criteria 2 and 3 .Biogen Idec might incur charges, realize gains or encounter other events in 2011 that might lead to actual results to change from this guidance. Recent Occasions Showcasing world-course R&D On October 26, 2011, Biogen Idec announced positive topline outcomes for CONFIRM, the next of two pivotal Stage III clinical trials made to measure the investigational oral substance BG-12 in people who have relapsing-remitting multiple sclerosis .