There also is an ongoing study of a different oligonucleotide against spinal muscular atrophy, and ongoing preclinical studies in Huntington's disease, myotonic dystrophy and other neurological disorders are in development. ‘The 1st person with ALS that I cared for experienced SOD1 ALS,’ she provides, ‘and I promised her a committed action to finding a treatment for this type of the disease. It's so gratifying to finally be at the stage of knowledge where we can start testing this treatment in sufferers with SOD1 ALS. We also hope that treatment might apply to the broader population of patient with sporadic ALS.’ Cudkowicz may be the Julieanne Dorn Professor of Neurology at Harvard Medical School..‘But nobody really understands exactly what this low-dose radiation does to the individual. We now have the technology that allows us to check out very subtle, cell-level changes.’ In the study, Wu’s group examined the blood of 67 people before and once they had undergone a heart CT scan . Following the scans, the research did show an increase in DNA damage in cells, as well as cell death. There was also improved expression of genes involved in the death or fix of cells, the study found. Many cells broken by the CT scan had been repaired, the researchers stated, but a small percent of them died. The bottom line: ‘We have now know that also exposure to smaller amounts of radiation from [CT] scanning is connected with cellular damage,’ research co-lead writer Dr.