Shortly after completing his rescue and recovery just work at the Globe Trade Center, Zadroga created a chronic cough, shortness of acid and breath reflux, Smith reported. He was suffering from headaches and nightmares. Within months, he required oxygen tanks, antibiotics and steroid shots regularly. November 2004 He retired on disability in. James, who was simply 6 foot 2 and weighed a lot more than 260 pounds before getting ill, had lost a lot more than 40 pounds by enough time his dad found him lifeless on his bedroom flooring in the house Jan.FOP is a uncommon, disabling genetic disease seen as a painful severely, recurrent episodes of smooth tissue swelling and new abnormal bone development. This process, referred to as heterotopic ossification , happens in muscles, tendons and ligaments, causing significant morbidities and progressive disability. Established under the Food and Drug Administration Modernization Action of 1997 , Fast Track designation is designed to facilitate the advancement and expedite the review of medications and biologic items that are designed to treat severe or life-threatening conditions, and that demonstrate the potential to address unmet medical requirements.